Summarizes the knowledge on memory mechanisms at the molecular, cellular and circuit level. This book discusses the memory mechanisms in the context of diseases. It introduces studies of memory deficits in disease models as well as approaches to restore memory deficits. It also illustrates the impact of contemporary memory research for psychiatry.

This book integrates discoveries from recent years to show the diversity of molecular mechanisms that contribute to memory consolidation, reconsolidation, extinction, and forgetting. It provides a special focus on the processes that govern functional and structural plasticity of dendritic spines. In nine chapters, new and important ideas related to learning and memory processes will be presented. Themes discussed include the role of AMPA receptors in memory, two signalling cascades involved in local spine remodelling and memory, the role of extracellular matrix proteins in memory, the...