When health officials in San Francisco discovered bubonic plague in their city's Chinatown in 1900, they responded with intrusive, controlling, and arbitrary measures that touched off a sociocultural conflict still relevant today. Guenter B. Risse's history of an epidemic is the first to incorporate the voices of those living in Chinatown at the time, including the desperately ill Wong Chut King, believed to be the first person infected.

Lasting until 1904, the plague in San Francisco's Chinatown reignited racial prejudices, renewed efforts to remove the Chinese from their district,...