Biophysical models have been used in biology for decades, but they have been limited in scope and size. In this book, Bernhard O. Palsson shows how network reconstructions that are based on genomic and bibliomic data, and take the form of established stoichiometric matrices, can be converted into dynamic models using metabolomic and fluxomic data. The Mass Action Stoichiometric Simulation (MASS) procedure can be used for any cellular process for which data is available and allows a scalable step-by-step approach to the practical construction of network models. Specifically, it can treat...
Biophysical models have been used in biology for decades, but they have been limited in scope and size. In this book, Bernhard O. Palsson shows how ne...
