Hypnosis, amnesia, and immobility are three major therapeutic endpoints of general anesthesia. In one to two cases out of a thousand, hypnosis and amnesia are not achieved often leaving a patient immobile but capable of experiencing and remembering intraoperative events. Awareness during general anesthesia is one of the most dreaded complications of surgery and is feared by patients and clinicians alike. Despite many advances in the field, there are also a number of unresolved questions that persist. Some of the difficulties in the detection and prevention of awareness during anesthesia...