In this edition we present the most common and important entities and diseases related with obstructive jaundice and provide the readers not only with the clinical and molecular advances but also to point out we are the future respective and what we will have to expect. We think that the presentation of the molecular basis of jaundice, the haemostasis impairment and immune dysfunction induced in obstructive jaundice helps in the deeper understanding of the benign and malignant diseases, their effects in the human body as well as in the value of the diagnostic modalities and the therapeutic...