This book constitutes selected revised papers of the 16th International Conference on Formalizing Natural Languages: Applications to Natural Language Processing and Digital Humanities, NooJ 2022, held in Rosario, Argentina, in June 2022. Due to COVID-19 pandemic the conference was held virtually.NooJ is a linguistic development environment that provides tools for linguists to construct linguistic resources that formalize a large gamut of linguistic phenomena: typography, orthography, lexicons for simple words, multiword units and discontinuous expressions, inflectional, derivational and...