This book constitutes the refereed proceedings of the 14th International Conference on ICT Innovations 2022. Reshaping the Future Towards a New Normal, ICT Innovations 2022, held in Skopje, Macedonia, during September 29–October 1, 2022.The 14 full papers and 1 short papers included in this book were carefully reviewed and selected from 42 submissions. They were organized in topical sections as follows: theoretical foundations and distributed computing; artificial intelligence and deep learning; applied artificial intelligence; education; and medical informatics.