This book constitutes the refereed proceedings of the 29th International Symposium on Static Analysis, SAS 2022, held in Auckland, New Zealand, in December 2022.The 18 full papers included in this book were carefully reviewed and selected from 43 submissions. Static analysis is widely recognized as a fundamental tool for program verification, bug detection, compiler optimization, program understanding, and software maintenance. The papers deal with theoretical, practical and application advances in the area.