The book contains selected research papers presented at the 2nd International Conference on Cyber-Physical Systems and Control (CPS&C’2021) which was held from 29 June to 2 July 2021 in St. Petersburg, Russia. The CPS&C’2021 Conference continues the series of international conferences that began in 2019 when the first International Conference on Cyber-Physical Systems and Control (CPS&C’2019) took place.Cyber-physical systems (CPSs) considered a modern and rapidly emerging generation of systems with integrated wide computational, information processing, and physical capabilities that...