This thesis explores the physics of non-equilibrium quantum dynamics in homogeneous two-dimensional (2D) quantum gases. Ultracold quantum gases driven out of equilibrium have been prominent platforms for studying quantum many-body physics. However, probing non-equilibrium dynamics in conventionally trapped, inhomogeneous atomic quantum gases has been a challenging task because coexisting mass transport and spreading of quantum correlations often complicate experimental analyses. In this work, the author solves this technical hurdle by producing ultracold cesium atoms in a quasi-2D optical box...