This book constitutes selected papers presented during the First International Conference on Deep Sciences for Computing and Communications, IconDeepCom 2022, held in Chennai, India, in March 2022.The 27 papers presented were thoroughly reviewed and selected from 97 submissions. They are organized in topical sections as follows: ​classification and regression problems for communication paradigms; deep learning and vision computing; deep- recurrent neural network (RNN) for industrial informatics; extended AI for heterogeneous edge.