This book constitutes the refereed proceedings of the Third Southern African Conference on  Artificial Intelligence Research, SACAIR 2022, held in Stellenbosch, South Africa, in  December 2022.The 26 papers presented were thoroughly reviewed and selected from the 73 submissions. They are organized on the topical sections on​ algorithmic, data driven and symbolic AI; socio-technical and human-centered AI; responsible and ethical AI.