This book constitutes thoroughly refereed and revised selected papers from the 10th Iberoamerican Conference on Applications and Usability of Interactive TV, jAUTI 2021, held in Sangolqui, Ecuador, during December 2–3, 2021.The 9 full papers included in this book were carefully reviewed and selected from 25 submissions. They were organized in topical sections as follows: ​Usability and UX; interaction techniques and accesibility; and technologies, services, and applications for interactive digital TV.