This book reviews, in one place, the breadth of articles that form the basis for the current practice of medicine. When physicians examine medical literature, there are articles that are quoted over and over again, as well as articles that have established the standards that are so embedded that we no longer think of where those standards came from. When clinicians treat patients with diabetes, why do we aim for an A1c less than 7%?  That standard comes primarily from two trials, the DPPT and the UKPDS trial, both of which broke new ground when they were published.  In addition, the ACCORD...