This textbook comprehensively covers the latest state-of-the-art methods and applications of artificial intelligence (AI) in medicine, placing these developments into a historical context. Factors that assist or hinder a particular technique to improve patient care from a cognitive informatics perspective are identified and relevant methods and clinical applications in areas including translational bioinformatics and precision medicine are discussed. This approach enables the reader to attain an accurate understanding of the strengths and limitations of these emerging technologies and how...