Systematically walks through computational methods devised to date (approximately between 2000 and 2016) for identifying protein complexes from the network of protein interactions (the protein-protein interaction (PPI) network). The authors present a detailed taxonomy of these methods, and comprehensively evaluate them for protein complex identification across a variety of scenarios.

Systematically walks through computational methods devised to date (approximately between 2000 and 2016) for identifying protein complexes from the network of protein interactions (the protein-protein interaction (PPI) network). The authors present a detailed taxonomy of these methods, and comprehensively evaluate them for protein complex identification across a variety of scenarios.