Describing the use of biophysical and biochemical methods to prove that calcium has a positive feedback effect on amplifying and sustaining CD3 phosphorylation and should enhance T-cell sensitivity to foreign antigens, this thesis couples the use of nuclear magnetic resonance (NMR) to the analysis of signaling phenomena in living cells.
Describing the use of biophysical and biochemical methods to prove that calcium has a positive feedback effect on amplifying and sustaining CD3 phosph...