Bee or wasp venom therapy is the therapeutic application of honeybee venom or wasp venom to the treatment of various diseases. Venoms from either honeybees or wasps are known to possess a wide variety of pharmaceutical properties. Recent studies using these venoms have demonstrated diverse mechanisms on a range of conditions. However, identification of a single constituent out of the venom, the possible mechanisms, and a justification of the route of application and formulation are essential in the future. Understanding the signalling pathways associated with the compound-mediated in vivo...