Research Paper (postgraduate) from the year 2016 in the subject Medicine - Human Genetics, language: English, abstract: Congenital heart disease (CHD) is an abnormality in the structure and function of the heart and great vessels caused by embryonic development disorders, it is highly complex and is not fully understood yet. This study performs a computational analysis of the nsSNPs in the GATA4 gene, to identify the possible mutations and propose a modeled structure for the mutant protein that potentially affects its function. The nsSNPs were analyzed using 5 prediction tools: SIFT,...
Research Paper (postgraduate) from the year 2016 in the subject Medicine - Human Genetics, language: English, abstract: Congenital heart disease (CHD)...