Exploring methods used to examine metal levels and distribution in brain tissue and cells, this book discusses the use of fluorescent metal probes, synchrotron-based X-ray microscopy, laser ablation-ICP-MS, laser-based tissue microdissection, MRI image analysis, fractionation of cell tissue samples for metal analysis and metal treatment of cells.

Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer's Disease, Parkinson's Disease, Motor Neuron Disease, Autism and lysosomal storage disorders.

This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration,...