This book focuses on the study of heavy quarkonium production at high-energy colliders as a useful tool to explain both the perturbative and non-perturbative aspects of quantum choromodynamics. It provides the first comprehensive comparison between the theory and recent experiments and clarifies some longstanding puzzles in the heavy quarkonium production mechanism. In addition, it describes in detail a new framework for implementing precise computations of the physical observables in quantum field theories based on recently developed techniques. It can be used to simulate the complicated...