This book aims to provide an up-to-date overview of the many signaling pathways regulating autophagy in response to different cellular needs. Discussion includes the current status and future directions of autophagy signaling research in different topics of health and disease. These include the roles of autophagy in regulating cell fate, immune response and host defense, nutrient sensing and metabolism, neural functions and homeostasis. The mechanisms and significance of cross-talk between autophagy and other cellular processes is also explored. Lastly, alterations in autophagy observed in...