This book provides a comprehensive advanced multi-linear algebra course based on the concept of Hasse-Schmidt derivations on a Grassmann algebra (an analogue of the Taylor expansion for real-valued functions), and shows how this notion provides a natural framework for many ostensibly unrelated subjects: traces of an endomorphism and the Cayley-Hamilton theorem, generic linear ODEs and their Wronskians, the exponential of a matrix with indeterminate entries (Putzer's method revisited), universal decomposition of a polynomial in the product of two monic polynomials of fixed smaller degree,...