Part I: The utility of some -acceptors as TCNQ, DCQ, DDB and -acceptor as I2 for spectrophotometric estimation of etamsylate and tranexamic acid drugs. Part II: It deals with the spectrophotometric determination of etamsylate drug via oxidation-reduction reaction using iodic acid. Part III: It deals with the spectrophotometric determination of tranexamic acid drug via Schiff base formation using salicylaldahyde. Thus the proposed methods can be used for routine analysis of the suggested drugs in pharmaceutical preparations."