Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality worldwide, and represents a huge and growing economic and social burden. COPD is a multi-factorial disorder caused by environmental determinants and genetic risk factors. The beta2-adrenergic receptor (β2-AR) mediates various physiologic responses of the airways. Alterations in the ADRB2 gene have a significant physiologic role in regulating responses to exogenous β2-agonists. Understanding the genetic predisposition of COPD is essential to develop personalized treatment regimens.
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality worldwide, and represents a huge and growing econ...
