Artemether (ART), the methylated derivative of artemisinin, is an efficacious antimalarial drug that also displays antischistosomal properties. This study was designed to evaluate the therapeutic action of single intramuscular dose (50 mg/kg body weight) of ART on S. mansoni infected mice. The parasitological studies showed that maximum effect was reached when ART treatment interfered with 14 or 21 days old schistosomula. This was reported as reduction in worm burden and distribution, female worm fecundity, oogram patturn and tissue ova count. However, ART showed fewer effects on adult worms....

Bancroftian filariasis is caused in human by Wuchereria (W.) bancrofti, which has major antigenic sharing with Dirofilaria (D.) immitis and Setaria (S.) equina. S. equina was used for diagnosis of bancroftian filariasis in human in comparison to D. immitis. Serological diagnosis of filariasis is generally more reliable than detection of microfilaria (mf) in blood samples. S. equina antigen was prepared from the adult worm. Fractionation of both whole S. equina crude antigen and imported D. immitis was done by polyacrylamide gel electrophoresis. The two antigens shared the same band pattern of...