Artemether (ART), the methylated derivative of artemisinin, is an efficacious antimalarial drug that also displays antischistosomal properties. This study was designed to evaluate the therapeutic action of single intramuscular dose (50 mg/kg body weight) of ART on S. mansoni infected mice. The parasitological studies showed that maximum effect was reached when ART treatment interfered with 14 or 21 days old schistosomula. This was reported as reduction in worm burden and distribution, female worm fecundity, oogram patturn and tissue ova count. However, ART showed fewer effects on adult worms....