Objective of the present study is to prolong the delivery of the active drug in the oral cavity using a suitable carrier such as in situ gels which can effectively deliver the drug for an extended duration of time hence not only reduce the systemic side effects but also improve the therapeutic efficacy, patient compliance. Local drug delivery systems are better suitable for antifungal drugs particularly for oral thrush. Over the past two decades, extensive research has been performed in the design of polymeric drug delivery systems. Among them, new series of thermosensitive, ion induced and...