Leprosy, also known as Hansen's disease, is an ancient disease retaining strong historic association with stigma. Almost everyone knows the word 'Leprosy' yet facts and fiction related to the disease are commonly confused. In spite of nearly three decades of intensive research into the immunology of leprosy, the mechanism by which M.leprae is able to elicit the entire range of human cellular immune responses has still not been explained. The spectrum of host response to M.leprae provides a model for investigating the role of a cytokine in the pathogenesis of mycobaterial disease. Ceramide, a...