The controlled release systems have captured the attention of many researchers due to their properties and functions that they may have in complex clinical treatments. Therefore, through different studies their applicability in formulations based on controlled release has been demonstrated. In the field of anesthesia and intensive care they have gained attention because of several characteristics that distinguish them from the conventional treatments. Among this we mention bioavailability, biodegradability, low toxicity and not least the increased capacity of biofunctionalization in...