The edgewise appliance has endured the test of time. This "worthwhile" invention has evolved from its inventor, Edward H. Angle, who was determined to use it to correct malocclusions while preserving "the full complement of teeth,". Charles H. Tweed who, after countless failures, introduced the extraction of four first premolars and anchorage preparation to produce facial balance. It continues through years of achievements to date and will continue in its successors benefiting countless patients. This book explains basic principles of standard edgewise technique.

Platelets play an important role in periodontal regeneration as they contain growth factors and cytokines which are essential for bone regeneration and soft tissue maturation. Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are autologous platelet concentrates prepared from patients own blood. PRF is second generation platelet concentrate which is prepared without any artificial biochemical modification of blood. It is biocompatible, easy to prepare, economical and enriched with platelets and growth factors. This book reviews the properties of PRF and its potential role in...