The aim of the study was to prepare and evaluate floating in-situ gel of methotrexate to increase the gastric residence time resulting in sustained drug release in gastrointestinal tract. Methotrexate is anticancer drug. It shows the undesirable side effect due to their fast release in the gastrointestinal tract (GIT). Floating in situ gel was prepared by using in-situ gel forming polymers like sodium alginate and pectin. Drug-excipients compatibility was carried out by FT-IR study. A 3level 2factor full factorial design was applied to investigate the combined effect of sodium alginate...
The aim of the study was to prepare and evaluate floating in-situ gel of methotrexate to increase the gastric residence time resulting in sustained dr...
The book with title Formulation and Evaluation of Fast Dissolving Film of Lamotrigine included Fast dissolving film is the oral film intended to be dissolved in mouth to ensure quick release of medicament. Fast dissolving film of anti-epileptic drug Lamotrigine which release the drug in a second to treat emergency condition occurred due to epilepsy.Faster onset of action in bipolar disease and in epileptic condition.
The book with title Formulation and Evaluation of Fast Dissolving Film of Lamotrigine included Fast dissolving film is the oral film intended to be di...