Melatonin is a natural hormone originating from the pineal gland. It has a circadian secretion pattern with highest concentrations during the night. Intense research during the past 20-30 years has revealed that when melatonin is given in supra-physiologic doses, i.e. as tablets in milligram doses, it has a number of very important effects. Thus, melatonin can be used for various sleep disorders including insomnia, and circadian disturbances such as shiftwork and jetlag. Melatonin is the strongest known antioxidant drug with effects in cardiac disease, cancer, depression, brain damage such as...