This book reviews the brilliant progress made in the past three decades in clinical outcomes for osteosarcoma patients treated with a multidisciplinary approach, including limb-salvage surgery combined with neoadjuvant multidrug chemotherapy and aggressive management of pulmonary metastasis.

Today,we encountere various social issues. , such as a natural disaster, war, and an economically stratified society, About That,The mass media makes a fuss each time. However, like the impermanence of the thought of Buddhism , society has repeatedly generated change from the old days. In the meaning, the society may be a change and the time of the turning point anytime. Because human beings are always exposed to crises. even if you consider only the phenomenon of society , it will be difficult to find the ideal model to overcome a crisis of the human nature. The main theme of this book is...