There is a continuous request for reliable, portable and rapid analytical devices which are inexpensive and capable of sensitive/selective detection in the area of diagnostic applications. In biosensing domain, to date, many different complex techniques from the most advanced categories have been developed and introduced to the scientific world. When the actual clinical practice is concerned, however, only minor percentages of such complex systems are applicable in routine analytical procedures. Such clear fact should lead and inspire researchers as well as industry to dedicate their attempts...