This book contains two parts. Part A] deals with preparation, characterisation of polymer loaded simvatstain nanoparticles and its antihyperlipidemic activity. Part B] of this chapter contains RP-HPLC method development and validation of simvastatin from bulk drug, tablet formulation and nanoparticles. In this study, simvastatin Np (SNp) formulations comprising SV were developed using different proportions of polymer. Here, we used nanoprecipitation method to prepare SV loaded nanoparticles. Other methods have also been accounted in previous years for SV Np and microparticles, however, no...