The thesis describes the development of receiver technologies for sub-millimetre astronomy instruments, focusing on high performance coherent cryogenic detectors operating close to the superconductor gap frequency. The mixer chip which comprises the SIS devices, fed by a unilateral finline and matching planar circuits was fabricated on 15 micron silicon substrate using the recently developed Silicon-On-Insulator (SOI) technology. This offered broadband IF and RF performance, with fully integrated on-chip planar circuits resulting in an easily reproducible mixer chip and a simple mixer block....