Factorial design as optimization technique was applied in formulation development and processing conditions of Diclofenac sodium granules. The present study involves design and evaluation of non-effervescent granules of Diclofenac sodium with excellent flow properties. In the formulation of non-effervescent granules of Diclofenac sodium, angle of repose was the dependent variable (with excellent flow) and the concentrations of binder (Povidone K-30) and lubricant (Magnesium stearate) were the two independent variables chosen at two different levels. With the help of factorial approach, a...
Factorial design as optimization technique was applied in formulation development and processing conditions of Diclofenac sodium granules. The present...