This book constitutes the proceedings of the 6th International IFIP Working Conference on Enterprise Interoperability, IWEI 2015, held in Nimes, France, in May 2015. The event was organized by the IFIP Working Group 5.8 on Enterprise Interoperability in co-operation with INTEROP-VLab and PGSO (Pole Grand Sud Ouest) from INTEROP-Vlab. The theme for IWEI 2015 was From Enterprise Interoperability Modelling and Analysis to Enterprise Interoperability Engineering. The 9 full, 4 short, and 2 industrial papers presented in this volume were carefully selected from 20 submissions. The selection was...