The discovery of imidazoline binding sites has broadened the horizon of drug development for the treatment of physiological and psychological conditions. The pharmacology of these sites has been extensively researched over the past few years. However, one of the puzzling questions that remains uncertain is the identity of an endogenous ligand for these binding sites. The beta-carboline harmane has been identified as the bioactive constituent of clonidine-displacing substance. The objective of this work was to investigate the neurotransmitter properties of harmane examining its uptake and...