Miconazole nitrate were used as antifungal agent, The main aim of this research study was to formulate transdermal patch of miconazole nitrate and it is evaluted for its surface endurance, thickness, moisture content, surface pH and in vitro release and its comparative study with marketed formulation. We finds better results in all respects of pH, surface endurance, moisture content, in vitro release pattern of drug from the transdermal patch and also compared to marketed preparation of miconazole nitrate. finally concluded that the prepared transdermal patch should be beneficial in all...

Oral route of drug delivery system has become ever more important as pharmaceutical scientists acquire a better understanding of physio-chemical and biological aspects related to their performances. Matrix and sustained release formulations have further added new realms in conventional drug delivery. Emerging megaloporous inert matrix system can be viewed principally as a single-unit device that comprises two phases, which operate together to regulate the drug release from the dosage form with a constant rate to the dissolution liquids over an extended period of time. One of the structures is...

Mucoadhesion of the developed formulations will provide a longer period of residence time reducing loss of drug by swallowing, which should result in higher bioavailability.The mucoadhesive tablets of cefuroxime axetil can prolong release of drug across the mucous membrane of intestine and can increase residence time of drug. That can improve its bioavailability and may reduce its dosing frequency and side effects.