The main aim of the present study was to formulate transdermal patch of Terminaliaarjuna bark extract for control drug delivery system in CVS disorders. Extraction of Terminaliaarjuna bark was done by using maceration technique whereas quantitative estimation of arjunolic acid was performed by using titration method extract. From the preliminary phytochemical test it was found that the alkalis, cardiac glycoside, tannins, tri terpenoids and saponins present in extract. In order to predict the optimum performance of prepared transdermal patch of Terminaliaarjuna we adopted a 32 factorial...