The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective...
The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second me...
This detailed volume encompasses new technological developments that specifically address questions related to adenosine 3,5 -monophosphate (cAMP) compartmentalization, that probe relevant protein-protein interactions, that increase the spatial and temporal resolution of cAMP signal detection, and that can facilitate integration of the mounting complexity of the information that is becoming available on this signaling system. cAMP, the prototypical intracellular second messenger, regulates a large variety of cellular functions and biological processes, including gene transcription, cell...
This detailed volume encompasses new technological developments that specifically address questions related to adenosine 3,5 -monophosphate (cAMP) ...
This detailed volume encompasses new technological developments that specifically address questions related to adenosine 3′,5′-monophosphate (cAMP) compartmentalization, that probe relevant protein-protein interactions, that increase the spatial and temporal resolution of cAMP signal detection, and that can facilitate integration of the mounting complexity of the information that is becoming available on this signaling system. cAMP, the prototypical intracellular second messenger, regulates a large variety of cellular functions and biological processes, including gene...
This detailed volume encompasses new technological developments that specifically address questions related to adenosine 3′,5′-monophos...
This volume discusses the latest techniques used by researchers to measure cAMP activity at the cell population, whole cell, and subcellular level. The techniques covered in the book address questions related to cAMP compartmentalization, which look at relevant protein-protein interactions that increase the spatial and temporal resolution of cAMP signals detection, and that can help in the integration of the increasingly complex information that is becoming available in this field. Written in the highly successfulMethods in Molecular Biologyseries format, chapters include introductions to...
This volume discusses the latest techniques used by researchers to measure cAMP activity at the cell population, whole cell, and subcellular level. Th...