This book discusses the global researches in the field of tumor angiogenesis. Angiogenesis is an extension process of the cardiovascular system within human body. It is mostly instigated by the need for oxygen and nutrients by the fast growing tissue and uncontrollably dividing cells, as observed during wound healing and tumor progression. This book emphasizes on tumor angiogenesis and presents topics written by highly experienced scholars from different countries. The objective of this book is to provide readers with an insight into the molecular and cellular mechanisms of this biological...

This is a comprehensive book which aims to present state-of-the-art information regarding microangiopathy. Microangiopathies are pathological processes which cause degenerative diseases of small vessels. The circulatory constraints caused by microangiopathies may be accountable for the collapse of single or multiple organs. These pathological processes are one of the most common disorders characterized by high morbidity and mortality in the affected patients. Various research outcomes have reflected intricate processes both at cellular and molecular level. However, the diversity among varied...

This book discusses the novel frontiers in the processes of vasculogenesis and angiogenesis. Vasculogenesis is the process of formation of new blood vessels when embryonic development of the cardiovascular system takes place. Formation of a vascular tree and finally, the cardiovascular system, with a mesh of blood vessels - that has a role in the nourishment of all tissues and organs - follows this process. Angiogenesis is the process involving evolution of new blood vessels from existing blood vessels by "sprouting" of endothelial cells, thereby expanding the vascular tree. Both of these...

Extensive information regarding the topic of tumor angiogenesis has been compiled in this advanced book. Tumor angiogenesis is the procedure primarily responsible for the generation of new blood vessels that boost tumor development and metastasis. The process is directed by potential pro-angiogenic factors that are prevalent in the tumor environment and are generated by malignant cells as well as the host cells recruited to the tumor site. Tumor environment is distinguished by the imbalance between anti-angiogenic and pro-angiogenic agents, which directs the formation of several, albeit...