The current book represents an elaborated study of the etiology and pathophysiology of Parkinson's disease, which is a complex neurological disorder. In this book, the ecological and biological agents which become the cause of Parkinson's disease have been described in detail. Other than genetic aspects, pathophysiological aspects of the disease have also been explained. Written by teachers of well reputed academic institutions the book highlights both primary and clinical approaches of Parkinson's disease. This book will be of great use for scientists and researchers. Also, neuroscience...

The current book represents an elaborated study of the etiology and pathophysiology of Parkinson's disease, which is a complex neurological disorder. In this book, the ecological and biological agents which become the cause of Parkinson's disease have been described in detail. The book provides detailed description to readers about latest developments in several branches like neurotransmitters, inflammatory responses, oxidative pathways and biomarkers. Written by teachers of well reputed academic institutions the book highlights both primary and clinical approaches of Parkinson's disease....

This book on Parkinson's disease provides latest information pertaining to topics associated with this disease, including research, early biomarkers for the diagnostics, and latest applications of brain imaging to analyze Parkinson's disease. Researchers have currently started to focus on the non-motor symptoms of this disease, which are poorly identified and insufficiently treated by clinicians and have a considerable effect on the quality of life of the patient and mortality and include autonomic, sensory and gastrointestinal symptoms, and cognitive impairments. Detailed discussion of the...

This book is a detailed, applicable and step-by-step medium helping students and researchers tounderstand Parkinson's disease. It provides the latest information pertaining to topics associated with this disease, including etiology, new methodologies to examine symptoms, multidisciplinary rehabilitation and invasive techniques to analyze Parkinson's disease. Researchers have currently started to focus on the non-motor symptoms of this disease, which are poorly identified and insufficiently treated by clinicians and have a considerable effect on the quality of life of the patient and mortality...

This book on Parkinson's disease (PD) elaborates the state-of-the-art research in the field. PD is caused mainly due to the death of dopaminergic neurons in the substantia nigra. Recent PD medications treat symptoms; though none decrease the rate of dopaminergic neuron degeneration. The primary problem in development of neuroprotective therapies is a restricted comprehension of the crucial molecular mechanisms that incite neurodegeneration. The discovery of PD genes has led to the hypothesis that dysfunction of the ubiquitin-proteasome pathway and misfolding of proteins are both critical to...

Various therapeutic modalities and treatments of Parkinson's disease (PD) have been described in this book. This disease is caused mainly due to the death of dopaminergic neurons in the substantia nigra. Recent PD medications treat symptoms; though none decrease the rate of dopaminergic neuron degeneration. The primary problem in development of neuroprotective therapies is a restricted comprehension of the crucial molecular mechanisms that incite neurodegeneration. The discovery of PD genes has led to the hypothesis that dysfunction of the ubiquitin-proteasome pathway and misfolding of...

The novel treatments in the field of Parkinson's disease (PD) are discussed in this book. Recent Parkinson's disease medications treat symptoms; though none decrease the rate of dopaminergic neuron degeneration. Parkinson's disease is caused mainly due to the death of dopaminergic neurons in the substantia nigra. The primary problem in development of neuroprotective therapies is a restricted comprehension of the crucial molecular mechanisms that incite neurodegeneration. The discovery of PD genes has led to the hypothesis that dysfunction of the ubiquitin-proteasome pathway and misfolding of...

The advanced therapies in the field of Parkinson's disease (PD) are discussed extensively in this book. This disease is clinically characterized by distinct progressive motor and non-motor symptoms, pathologically due to loss of dopamine generating cells and intra-neuronal cytoplasmic inclusions comprised mainly of synuclein. A considerable proportion of the cells in the substantia nigra are already lost before patients are first diagnosed with even the earliest symptoms of PD at the clinic. This damage continues irrespective of the available therapies until the cell loss is so high that the...