An elucidative account based on muscle cells and tissues has been presented to the readers in this book. It deals with basic aspects of contractile mechanism in skeletal and smooth muscle cells and also the function of melanocytes, which possess many properties common to those of smooth muscles. It also covers pathological aspects of cardiac and smooth muscle cell functions along with dealing with factors influencing structure and function of cardiac and smooth muscle cells and tissues. The content of this book is thought-provoking and informative for readers interested in basic, pathological...

The increased knowledge of the genetic basis of a broad range of muscle diseases has led to a dramatic alteration in the investigation of muscle diseases. Muscle biopsy has become a strong instrument not just to provide diagnosis, but to make tissue accessible for genetic studies, and to elementary scientists for biomedical research, as well as to examine mitochondrial dysfunction and the mitochondrial DNA integrity in oxidation. Precise interpretation of muscle biopsy to catch cell dysfunction/damage/death or absence/abnormality of a protein or genetic defect by the sophisticated...

With over 30 distinct types as well as subtypes known and several more to be recognized and sorted, muscular dystrophy is an extremely heterogeneous group of inherited neuromuscular disorders. The book presents an elaborative analysis of the different types of muscular dystrophies, genes related to each subtype, disease diagnosis, management as well as available treatment options. Though every distinct type and subtype of muscular dystrophy is related to a distinct causative gene, most of them have overlapping clinical presentations, making molecular diagnosis certain for both patient...

Muscular dystrophy is an extremely heterogeneous group of inherited neuromuscular disorders with over 30 distinct types as well as subtypes known and several more to be recognized and sorted. The book presents an elaborative analysis of the different types of muscular dystrophies, genes related to each subtype, disease diagnosis, management as well as available treatment options. Although every distinct type and subtype of muscular dystrophy is related to a distinct causative gene, most of them have overlapping clinical presentations, making molecular diagnosis certain for both patient...