The aim of the present study was extract pure ketamine powder from ketamine hydrochloride solution; ketamine gel in different concentrations was prepared to detect the therapeutic effectiveness of it as analgesic in the form of a topical application in both human and laboratory animals.The results demonstrated that the purified ketamine was pure according to IR, UV, CHN analysis and melting point. Ketamine gel also is safe to be used topically and not irritant according to the skin irritation test, because the mean value of skin irritation index (SII) for erythema and edema was found to be...

A new calcium based cement, followed by evaluation of its physical, mechanical, biological and antimicrobial properties, comparing the results with other base restorative material (polycarboxylate cement and biodentine) under the american national standard institute specification number 96 for water based cement.The powder of the new cement was prepared from chicken egg shell while the liquid was polyacrylic acid, more than three thousands four handared formulas were trialed until we reach the appropriate one.The reaction of cement was confirmed by Fourier transform infra-red spectroscopy and...