Pyridazine derivatives have received much attention due to their reactions. Since, many pyridazine derivatives possess potential therapeutic effects, one can expect that replacement of a heterocyclic aromatic moiety in a bioactive molecule with the pyridazine nucleus would alter the physiochemical characteristics of that molecule significantly. Literature surveys showed that triazole, thiazole and thiophene derivatives, which are both commercially available drugs and agents under clinical investigations were the subject of a comprehensive review. On the other hand, Sulfonamides and...

Azo compounds have for a great many years occupied a dominant position in the field of coloring matters due to their versatility. A large volume of publications and patents have appeared describing their synthesis and dyeing properties. Among these, azo dyes using heterocyclic amines have become important as they give brighter and stronger results than those based on aniline-based diazo compounds. The pyrazole derivatives based azo dyes are known as disperse dyes with excellent brightness of shade. This class of dyes was established as an alternative to the more expensive anthraquinone dyes....

Pyridazine and pyrazole ring systems are known to possess potent biological and pharmacological properties. On the other hand some pyridazines derivatives are used as key starting material for the synthesis of commercial dyes. Acetylacetone, ethyl acetoacetate and malononitrile were coupled with diazotized arylamines to give arylazoacetylacetones, ethyl arylazoacetoacetates and arylazomalononitriles; these when refluxed with 5,6-diphenyl-2,3-dihydro-3-oxopyridazine-4-carbohydrazide, 3-amino-4,5-diphenyl-1H-pyrazolo 3,4-c]pyridazine and 3-hydrazino-4,5-diphenyl-1H-pyrazolo 3,4-c]pyridazine...