Metalloproteins, which contain metal atoms at their active sites, are involved in many biological processes. Nearly half of all proteins require the presence of a metal atom to function, and thus, the metalloprotein is a new hot focus of chemical biology and biomedical science. This review volume addresses the most exciting current research on metalloproteins & metalloenzymes, according to their functional category. It hereby thoroughly devotes developments on substance synthesis, signal transduction, gene regulation, drug metabolism, redox catalysis, catalytic hydrolysis, metal trafficking,...