Chemicals causing Endocrine disruptors are present in the environment and they have anti-androgenic and/or estrogen likes properties that cause deleterious effect on the male reproductive system resulting in infertility and erectile dysfunction (ED). These estrogen like or anti-androgenic chemicals are called endocrine disruptors because they either intimate the structure of natural hormones, causes the inhibition of action of the hormones or produces changes in the normal hormonal regulation of the endocrine system. Many pesticides with endocrine disrupting properties are known to adversely...

The modern man is constantly exposed to a variety of toxic chemicals primarily due to changes in life style. Among all classes of pesticides, carbamates are most commonly used compounds because OPs and OCls are extremely toxic and possess delayed neurotoxic effects. Toxicological characteristics of the N-methyl carbamates involve maximal cholinesterase enzyme inhibition followed by a rapid recovery, typically from minutes to hours. Among other pesticides, carbamates have been included in the list of known endocrine disruptor compounds.The accumulation of carbofuran in animals and humans may...